Bio 296C/CSc 296N
Bioinformatics

Syllabus

Schedule

Prerequisite

Grading

Course Description

This course will introduce the basic computational issues and methods used in molecular biology and molecular genetics. It combines lectures, programming assignments, with midterm and final. It teaches how to make biological inferences from DNA and protein sequences using computing techniques that include structural and functional genomics, pairwise sequence alignment, multiple sequence alignment, gene recognition, genetic regulation, homology modeling. It also teaches relevant statistical models, algorithms, Perl programming in the UNIX environment, and accessing biological databases using software tools.

Lecture: Tu and Th, 12:00 - 12:50 pm; Lab: Tu, 1:00-2:40 pm
Jim Keller's Lab Assistant Hours: Th 1:45-3:45 pm, Fri 12:00-2:00 pm
Student course project web pages

1. Cynthia Gibas, Per Jambeck. Developing Bioinformatics Computer Skills. O'Reilly & Associates; ISBN: 1565926641 April 2001.
2.  Robert W. Sebesta. A Little Book on Perl. Prentice Hall; ISBN: 0139279555, December 1999, recommended for new Perl programmer only.
3. The Internet for Molecular Biologists, Sansom, C.E. and Horton, R.M., eds. Oxford University Press, Practical Approach Series, (in press).
4.  Horton, R.M. Sickle Cell Anemia: A Molecular Disease. Cybertory^TM Virtual Molecular Biology Laboratory Manual, Attotron Biosensor Corporation, 1999.

 Additional references and recommended readings

Developing a Bioinformatics Program
Bioinformatics Resources on the World Wide Web
Bioinformatics Resources and Tools
Bioinformatics web links for Community College Teachers
How Perl Saved the Human Genome Project
Retooling for Bioinformatics

General Interests

WWWebster Dictionary

Grammar Help